Meng, Fanke   Professor

State Key Laboratory of Organometallic Chemistry

Shanghai Institute of Organic Chemistry, CAS

345 Lingling Lu, Shanghai 200032

Phone/Fax: +86 21 54925203

Email: mengf@sioc.ac.cn

Education:

2010-2015 Ph.D., Boston College (Advisor: Prof. Amir H. Hoveyda)

2006-2010 B.S., Peking University (Advisor: Prof. Zhen Yang and Prof. Jiahua Chen)

Academic Career:

2016-present: Professor, State Key Laboratory of Organometallic Chemistry, SIOC

2015-2016: Postdoctoral Research Associate, Boston College (Advisor: Prof. Amir H. Hoveyda)

Awards & Honors:

2019 Thieme Chemistry Journals Award
2014 Chinese Government Award for Outstanding Self-Financed Students Abroad
2014-2015 Bristol-Myers Squibb Graduate Fellowship in Synthetic Organic Chemistry
2013-2014 John LaMattina Fellowship, Boston College

Research Interest

Enantioselective Cobalt-Catalyzed Reactions

First-Row Transition Metal-Catalyzed Reactions

Organoboron Chemistry

Application to Biologically Active Small Molecule Synthesis

Selected Publications

1. Zhang, H.; Huang, W.; Wang, T.; Meng, F.* “Cobalt-Catalyzed Diastereo- and Enantioselective Hydroalkenylation of Cyclopropenes with Alkenylboronic Acids” Angew. Chem. Int. Ed. 2019, 58, 11049.

2. Cheng, F.; Lu, W.; Huang, W.; Wen, L.; Li, M.; Meng, F.* “Cu-Catalyzed Enantioselective Synthesis of Tertiary Benzylic Copper Complexes and Their in situ Addition to Carbonyl Compounds”, Chem. Sci. 2018, 9, 4992

3. Wen, L.; Cheng, F.; Li, H.; Zhang, S.; Hong, X.; Meng, F.* “Cu-Catalyzed Enantioselective Hydroboration of 1,1-Disubstituted Alkenes: Method Development, Applications and Mechanistic Studies.” Asian J. Org. Chem. 2018, 7, 103.

4. Chong, Q; Yue, Z.; Zhang, S.; Ji, C.; Cheng, F.; Zhang, H.; Hong, X.; Meng, F.* “N-Heterocyclic Carbene–Cu-Catalyzed Enantioselective Conjugate Addition with Alkenylboronic Esters as Nucleophiles” ACS Catal. 2017, 7, 5693.

5. Wen, L.; Yue, Z.; Zhang, H.; Chong, Q.; Meng, F.* “Cu-Catalyzed Enantioselective Boron Addition to N-Heteroaryl-Substituted Alkenes” Org. Lett. 2017, 19, 6610.

6. Meng, F.; Li, X.; Torker, S.; Shi, Y.; Hoveyda, A. H. “Catalytic Enantioselective 1,6-Conjugate Additions of Propargyl and Allyl Group,” Nature 2016, 537, 387.

7. Li, X.; Meng, F.; Torker, S.; Shi, Y.; Hoveyda, A. H. “Multicomponent Catalytic Enantioselective Conjugate Addition Reactions Involving Allylcopper Intermediates Derived from Butadiene and Isoprene,” Angew. Chem. Int. Ed. 2016, 55, 9997.

8. Meng, F.; McGrath, K. P.; Hoveyda, A. H. “Multifunctional Organoboron Compounds for Scalable Natural Product Synthesis,” Nature 2014, 513, 367. (Highlighted in Nature, Nature Chemistry and C&EN News).

9. Meng, F.; Haeffner, F.; Hoveyda, A. H. “Diastereo- and Enantioselective Reactions of Bis(pinacolato)diboron, 1,3-Enynes, and Aldehydes Catalyzed by an Easily Accessible Bisphosphine–Cu Complex,” J. Am. Chem. Soc. 2014, 136, 11304.

10. Meng, F.; Jang, H.; Jung, B.; Hoveyda, A. H. “Cu-Catalyzed Chemoselective Preparation of 2-(Pinacolato)boron-Substituted Allylcopper Complexes and their In Situ Site-, Diastereo-, and Enantioselective Additions to Aldehydes and Ketones,” Angew. Chem., Int. Ed. 2013, 52, 5046.