Ding, Kuiling 　Professor

State Key Laboratory of Organometallic Chemistry

Shanghai Institute of Organic Chemistry, CAS

345 Lingling Lu, Shanghai 200032

Phone: +86 21 54925146

Fax: +86 21 64166128

Email: kding@sioc.ac.cn

Education:

09/1987 - 10/1990  Ph.D. (Organic Chemistry), Dept. of Chem., Nanjing University(with Professor Yangjie Wu)

07/1985 - 09/1987　Master course (Organic Chemistry), Dept. of Chem., Zhengzhou University (with Prof. Yangjie Wu)

09/1981 - 07/1985  B.Sc. (Chemistry), Dept. of Chem., Zhengzhou University
Academic Career:

12/1998 - present　Research Professor at Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences.

08/2003 - 11/2003　Visiting Professor at Research Center of Material Science, Nagoya University, Japan.

12/1995 - 11/1998　Full Professor at Department of Chemistry, Zhengzhou University

09/1997 - 09/1998　UNESCO research fellow at Tokyo Institute of Technology, Japan (with Prof. Koichi Mikami)

11/1992 - 11/1995　Associate Professor at Department of Chemistry, Zhengzhou University

09/1993 - 09/1994　Postdoctoral Fellow at Ryukoku University, Japan(with Prof. Teruo Matsuura)

10/1990 - 10/1992　Assistant Professor at Department of Chemistry, Zhengzhou University

 

International Journal & Conference Service

International Advisory Board Member of Eur. J. Org. Chem.(2006-)

International Advisory Board Member of Chem. Commun.(2008-)

Advisory Board Member of International Symposium on Homogeneous Catalysis (ISHC, 2006, 2008, 2010)

 

Awards & Honors:

State Award for Natural Sciences, Second-Class (2009)

Shanghai Award for Natural Sciences, First-Class (2008)

Shanghai Young Talents in Science and Technology (2006)

Zhuang Changgong Academic Award, Shanghai Society of Chemistry and Chemical Industry (2006)

Excellent Supervisor Award, Graduate School of Chinese Academy of Sciences (2006)

Synlett/Synthesis Journal Awardee  (2005)

First-Class Award for Advancement of  Science and Technology, Henan Province (2002) (second author)

 

Research Interest:

Combinatorial approach to asymmetric catalysis

Development of new strategies for chiral catalyst immobilization

Development of novel chiral ligands for asymmetric catalysis

 

Selected Publications:

1. Mingyue Wu, Zhaobin Han, Kaizhi Li, Ji’en Wu, Kuiling Ding*, Yixin Lu*; Cyclohexyl-Fused, Spirobiindane-Derived, Phosphine-Catalyzed, Synthesis of Tricyclic γ-Lactams and Kinetic Resolution of γ？Substituted Allenoates, J. Am. Chem. Soc. 2019, 141, 16362-16373. 

2. Yao Ge, Zhaobin Han,* Zheng Wang, Kuiling Ding*; Ir-Catalyzed Double Asymmetric Hydrogenation of 3,6-Dialkylidene-2,5-diketopiperazines for Enantioselective Synthesis of Cyclic Dipeptides, J. Am. Chem. Soc. 2019, 141, 8981-8988.  

3. Linli Zhang, Yitian Tang, Zhaobin Han,* Kuiling Ding*; Lutidine-Based Chiral Pincer Manganese Catalysts for Enantioselective Hydrogenation of Ketones, Angew. Chem. Int. Ed. 2019, 58, 4973-4977.  

4. Jia Qiu, Shen Gao, Chaopeng Li, Lei Zhang, Zheng Wang*, Xiaoming Wang, Kuiling Ding*; Construction of All-Carbon Chiral Quaternary Centers via Cu(I)-Catalyzed Enantioselective Reductive Hydroxymethylation of 1, 1-Disubstituted Allenes with CO2, Chem. Eur. J. 2019, 25, 13874-13878. 

5. Zhiyao Zheng, Yuxi Cao, Dongsheng Zhu, Zheng Wang*, Kuiling Ding*; Development of Chiral Spiro Phosphoramidites for Rhodium-Catalyzed Enantioselective Reactions, Chem. Eur. J. 2019, 25, 9491– 9497.  

6. Peihua Guo, Rui Zhang, Xiaoming Wang, Zheng Wang*, Kuiling Ding*; Synthesis of Chiral Tertiary a,a-Difluoromethyl Carbinols by Cu-Catalyzed Asymmetric Propargylation, Chem. Eur. J. 2019, 25, 16425-16434.  

7. Yao Ge, Zhaobin Han,* Zheng Wang, Chen-Guo Feng, Qian Zhao, Guo-Qiang Lin, Kuiling Ding*; Ir-SpinPHOX Catalyzed Enantioselective Hydrogenation of 3-Ylidenephthalides, Angew. Chem. Int. Ed. 2018, 57, 13140-13144.  

8. Zhiyao Zheng, Yuxi Cao, Qinglei Chong, Zhaobin Han, Jiaming Ding, Chenguang Luo, Zheng Wang, Dongsheng Zhu, Qi-Lin Zhou, Kuiling Ding*; Chiral Cyclohexyl-Fused Spirobiindanes: Practical Synthesis, Ligand Development, and Asymmetric Catalysis, J. Am. Chem. Soc. 2018, 140, 10374-10381. 

9. Xinyi Ren, Zhiyao Zheng, Lei Zhang, Zheng Wang, Chungu Xia*, Kuiling Ding*; Rhodium-Complex-Catalyzed Hydroformylation of Olefins with CO2 and Hydrosilane, Angew. Chem. Int. Ed. 2017, 56, 310-313.  

10. Xubin Wang, Xiaoming Wang, Zhaobin Han, Zheng Wang*, Kuiling Ding*; Palladium-Catalyzed Asymmetric Allylic Allylation of Racemic Morita–Baylis–Hillman Adducts, Angew. Chem. Int. Ed. 2017, 56, 1116-1119. 

11. Jiawang Liu, Zhaobin Han, Xiaoming Wang, Fanye Meng, Zheng Wang, Kuiling Ding*; Palladium-Catalyzed Asymmetric Construction of Vicinal Tertiary and All-Carbon Quaternary Stereocenters by Allylation of β-Ketocarbonyls with Morita-Baylis-Hillman Adducts, Angew. Chem., Int. Ed.  2017, 56, 5050-5054.  

12. Jiawang Liu, Ming Nie, Qinghai Zhou, Shen Gao, Wenhao Jiang, Lung Wa Chung, Wenjun Tang*, Kuiling Ding*; Enantioselective palladium-catalyzed diboration of 1,1-disubstituted allenes, Chem. Sci., 2017, 8, 5161-5165. 

13. Xubin Wang, Xiaoming Wang, Zhaobin Han, Zheng Wang*, Kuiling Ding*; Palladium-catalyzed asymmetric allylic amination: enantioselective synthesis of chiral α-methylene substituted β-aminophosphonates, Org. Chem. Front. 2016, 4, 271-276.   

14. Jiawang Liu, Zhaobin Han, Xiaoming Wang, Zheng Wang, and Kuiling Ding*; Highly Regio- and Enantioselective Alkoxycarbonylative Amination of Terminal Allene Catalyzed by a Spiroketal-Based Diphosphine/Pd(II) Complex, J. Am. Chem. Soc. 2015, 137, 15346-15349.

15. Yang Li, Zheng Wang, Kuiling Ding*; Minimizing Aryloxy Elimination in RhI-Catalyzed Asymmetric Hydrogenation of Aryloxyacrylic Acids using a Mixed-Ligand Strategy, Chem. Eur. J. 2015, 21, 16387-16390. 

16.  Lei Zhang, Zhaobin Han, Xiaoyu Zhao, Zheng Wang, Kuiling Ding*; Highly Efficient Ruthenium-Catalyzed N-Formylation of Amines with H2 and CO2, Angew. Chem. Int. Ed. 2015, 54, 6186-6189.