You, Shuli----State Key Laboratory of Organometallic Chemistry 345 Lingling Lu, Shanghai

You, Shuli　 Professor

State Key Laboratory of Organometallic Chemistry

Shanghai Institute of Organic Chemistry, CAS

345 Lingling Lu, Shanghai 200032

Phone: +86 21 54925085

Fax: +86 21 54925087

Email:slyou@sioc.ac.cn

Education:

09/1996 - 07/2001 Ph.D. (Advisor: Prof Lixin Dai), Shanghai Institute of Organic Chemistry

09/1992 - 07/1996 B.S. (Chemistry), Nankai University.

Research Experience:

04/2006 - present Professor, State Key Laboratory of OrganometallicChemistry, SIOC

02/2004 - 04/2006 Principal Investigator, Genomics Institute of the Novartis Research Foundation

09/2001 - 01/2004 Postdoctoral fellow, The Scripps Research Institute (Advisor: Prof. Jeffery W. Kelly)

Awards & Honors:

Xplorer Prize (2019)

2017/2018 Novartis Chemistry Lectureship

National Natural Science Award (2017, 2nd class, the first awardee)

Ho Leung Ho Lee Foundation Prize for Scientific and Technological Innovation (2016)

RSC Merck Award 2015

AstraZeneca Excellence in Chemistry Award (2011)

Research Interest:

Asymmetric catalysis

Organometallics

Selected Publications:

1. S.-L. You (2016)Asymmetric Dearomatization Reactions, Wiley-VCH.

2. S.-L. You (2015)Asymmetric Functionalization of C-H Bonds, Royal Society of Chemistry.

3. Zhang, X.;You, S.-L.*Asymmetric Allylic Substitution Reactions by Ir-Catalysts Derived from C(sp2)-H Activation of Chiral Ligands.Aldrichimica ACTA.2020,53, 11-18.

4. Xia, Z.-L.; Xuxu, Q.-F.; Zheng, C.*;You, S.-L.*Chiral phosphoric acid-catalyzed asymmetric dearomatization reactions.Chem. Soc. Rev.2020,49, 286-300.

5. Liu, X.-J.; Jin, S.; Zhang, W.-Y.; Liu, Q.-Q.; Zheng, C.;You, S.-L.*Sequence-Dependent Stereodivergent Allylic Alkylation/Fluorination Reaction of Acyclic Ketones.Angew. Chem. Int. Ed.2020,59, 2039-2043 (VIP).

6. Cheng, Y.-Z.; Zhao, Q.-R.; Zhang, X.*;You, S.-L.*Asymmetric Dearomatization of Indole Derivatives with N-Hydroxycarbamates Enabled by Photoredox Catalysis.Angew. Chem. Int. Ed.2019,58, 18069-18074.

7. Cai, Z.-J.; Liu, C.-X.; Wang, Q.; Gu, Q.*;You, S.-L.*Thioketone-Directed Rhodium(I) Catalyzed Enantioselective C-H Bond Arylation of Ferrocenes.Nat. Commun.2019,10, 4168.

8. Xia, Z.-L.; Zheng, C.*; Xu, R.-Q.;You, S.-L.*Chiral Phosphoric Acid Catalyzed Aminative Dearomatization of α-Naphthols/Michael Addition Sequence.Nat. Commun.2019,10, 3150.

9. Wang, Q.; Cai, Z.-J.; Liu, C.-X.; Gu, Q.;You, S.-L.*Rhodium-Catalyzed Atroposelective C–H Arylation: Efficient Synthesis of Axially Chiral Heterobiaryls.J. Am. Chem. Soc.2019,141, 9504-9510.

10.Liu, X.-J.; Zheng, C.; Yang, Y.-H.; Jin, S.;You, S.-L.*Iridium-Catalyzed Asymmetric Allylic Aromatization Reaction.Angew. Chem. Int. Ed.2019,58, 10493-10499.

11. Cheng, Q.; Xie, J.-H.; Weng, Y.-C.;You, S.-L.*Pd-Catalyzed Dearomatization of Anthranils with Vinylcyclopropanes via [4+3] Cyclization Reaction.Angew. Chem. Int. Ed.2019,58, 5739-5743 (hot article).

12. Zheng, C.*;You, S.-L.*Catalytic asymmetric dearomatization (CADA) reaction enabled total syntheses of indole-based natural products.Nat. Prod. Rep.2019,36, 1589-1605.

13. Wang, Y.; Zhang, W.-Y.;You, S.-L.*Ketones and Aldehydes as O-Nucleophiles in Iridium-Catalyzed Intramolecular Asymmetric Allylic Substitution Reaction.J. Am. Chem. Soc.2019,141, 2228-2232.

14. Zhu, M.; Zheng, C.*; Zhang, X.*;You, S.-L.*Synthesis of Cyclobutane-Fused Angular Tetracyclic Spiroindolines via Visible-Light-Promoted Intramolecular Dearomatization of Indole Derivatives.J. Am. Chem. Soc.2019,141, 2636-2644.

15. Cai, Z.-J.; Liu, C.-X.; Gu, Q.*; Zheng C.;You, S.-L.*Pd(II)-Catalyzed Regio- and Enantioselective Oxidative C-H/C-H Cross-Coupling Reaction between Ferrocenes and Azoles.Angew. Chem. Int. Ed.2019,58, 2149-2153.

16. Xia, Z.-L.; Zheng, C.*; Liang, X.-W.; Cai, Y.;You, S.-L.*Manipulation of Spiroindolenine Intermediates for the Enantioselective Synthesis of 3-(Indol-3-yl)pyrrolidines.Angew. Chem. Int. Ed.2019,58, 1158-1162.

17. Cheng, Q.; Hu, H.-F.; Zheng, C.; Qu, J.-P.; Helmchen, G.*;You, S.-L.*Iridium-Catalyzed Asymmetric Allylic Substitution Reactions.Chem. Rev.2019,119,1855-1969.

18. Huang, L.; Cai, Y.; Zhang, H.-J.; Zheng, C.; Dai, L.-X.;You, S.-L.*Chemoselective N-H Functionalization of Indole Derivatives via Reissert-type Reaction Catalyzed by Chiral Phosphoric Acid.CCS Chem.2019,1, 106-116.

19. Wang, Q.; Gu, Q.;You, S.-L.*Enantioselective Carbonyl Catalysis Enabled by Chiral Aldehydes.Angew. Chem. Int. Ed.2019,58, 6818-6825.

20. Zhang, M.-C.; Wang, D.-C.; Xie, M.-S.; Qu, G.-R.; Guo, H.-M.*;You, S.-L.*Cu-catalyzed Asymmetric Dearomative [3+2] Cycloaddition Reaction of Benzazoles with Aminocyclopropanes.Chem.2019,5, 156-167.

21. Yang, Z.-P.; Jiang, R.; Wu, Q.-F.; Huang, L.; Zheng, C.*;You, S.-L.*Iridium-Catalyzed Intramolecular Asymmetric Allylic Dearomatization Reaction of Benzene Derivatives.Angew. Chem. Int. Ed.2018,57, 16190-16193.

22.Xu-Xu, Q.-F.; Liu, Q.-Q.; Zhang, X.*;You, S.-L.*Copper-Catalyzed Ring Opening of Benzofurans and Enantioselective Hydroamination Cascade.Angew. Chem. Int. Ed.2018,57, 15204-15208.

23. Tu, H.-F.; Zhang, X.; Zheng, C.; Zhu, M.;You, S.-L.*Enantioselective dearomative prenylation of indole derivatives.Nature Catal.2018,1, 601-608. (Tu, H.-F. and Zhang, X. contribute equally)

24. Zheng, C.*; Xia, Z.-L.;You, S.-L.*Unified Mechanistic Understandings of Pictet–Spengler Reactions.Chem.2018,4, 1952-1966.

25. Tang, S.-B.; Zhang, X.; Tu, H.-F.;You, S.-L.*Regio- and Enantioselective Rhodium-Catalyzed Allylic Alkylation of Racemic Allylic Alcohols with 1,3-Diketones.J. Am. Chem. Soc.2018,140, 7737-7742.

26. Cheng, R.; Li, B.; Wu, J.; Zheng, J.; Qiu, Z.*; Tang, W.;You, S.-L.; Tang, Y.; Xie, Z.* Enantioselective Synthesis of Chiral-at-Cage o-Carboranes via Pd-Catalyzed Asymmetric B？H Substitution.J. Am. Chem. Soc.2018,140, 4508-4511.

27. Yang, Z.-P.; Jiang, R.; Zheng, C.*;You, S.-L.*Iridium-Catalyzed Intramolecular Asymmetric Allylic Alkylation of Hydroxyquinolines: Simultaneous Weakening the Aromaticity of Two Consecutive Aromatic Rings.J. Am. Chem. Soc.2018,140, 3114-3119.

28. Xia, Z.-L.; Zheng, C.*; Wang, S.-G.;You, S.-L.*Catalytic Asymmetric Dearomatization of Indolyl Dihydropyridines via Enamine Isomerization/Spirocyclization/Transfer Hydrogenation Sequence.Angew. Chem. Int. Ed.2018,57, 2653-2656.

29. Cheng, Q.; Zhang, F. Cai, Y.; Guo, Y.-L.*;You, S.-L.*Stereodivergent Synthesis of Tetrahydrofuroindoles via Pd-Catalyzed Asymmetric Dearomative Formal [3+2] Cycloaddition Reactions.Angew. Chem. Int. Ed.2018,57, 2134-2138.

30. Cai, Z.-J.; Liu, C.-X.; Gu, Q.;You, S.-L.*Thioketone Directed Palladium(II)-Catalyzed C-H Arylation of Ferrocenes with Aryl Boronic Acids.Angew. Chem. Int. Ed.2018,57, 1296-1299.

31. Zhang, X.;You, S.-L.*Removing the Mask in Catalytic Asymmetric Diamination of Alkenes.Chem.2017,2, 917-929.

32. Wang, Y.; Zheng, C.*;You, S.-L.*Ir-Catalyzed Asymmetric Allylic Dearomatization via a Desymmetrization Strategy.Angew. Chem. Int. Ed.2017,56, 15093-15097. (VIP)

33. Huang, L.; Cai, Y.; Zheng, C.; Dai, L.-X.;You, S.-L.*Iridium-Catalyzed Enantioselective Synthesis of Pyrrole-Annulated Medium-Sized-Ring Compounds.Angew. Chem. Int. Ed.2017,56, 10545-10548.

34. Cheng, Q.; Zhang, H.-J.; Yue, W.-J.;You, S.-L.*Palladium-Catalyzed Highly Stereoselective Dearomative [3+2] Cycloaddition of Nitrobenzofurans.Chem.2017,2, 428-436.

35. Wang, S.-G.; Xia, Z.-L.; Xu, R.-Q.; Liu, X.-J.; Zheng, C.;You, S.-L.*Construction of Chiral Tetrahydro-β-Carbolines through Asymmetric Pictet-Spengler Reaction of Indolyl Dihydropyridines.Angew. Chem. Int. Ed.2017,56, 7440-7443. (Wang, S.-G. and Xia, Z.-L. contribute equally)

36. Xu, R.-Q.; Gu, Q.;You, S.-L.*Construction of Benzomesembrine Skeleton via Pd(0)-Catalyzed Intermolecular Arylative Dearomatization of α-Naphthols and Aza-Michael Cascade.Angew. Chem. Int. Ed.2017,56, 7252-7256.

37. Zheng, J.; Wang, S.-B.; Zheng, C.;You, S.-L.*Asymmetric Synthesis of Spiropyrazolones via Rh-Catalyzed C(sp2)？H Functionalization/Annulation Reactions.Angew. Chem. Int. Ed.2017,56, 4540-4544.

38. Liu, X.-J.;You, S.-L.*Enantioselective Iridium-Catalyzed Allylic Substitution with 2-Methylpyridines.Angew. Chem. Int. Ed.2017,56, 4002-4005.

39. Gao, D.-W.; Gu, Q.; Zheng, C.;You, S.-L.*Synthesis of Planar Chiral Ferrocenes via Transition-Metal-Catalyzed Direct C–H Bond Functionalization.Acc. Chem. Res.2017,50, 351-365.

40. Tu, H.-F.; Zheng, C.; Xu, R.-Q.; Liu, X.-J.;You, S.-L.*Ir-Catalyzed Intermolecular Asymmetric Dearomatization of β-Naphthols with Allyl Alcohols or Allyl Ethers.Angew. Chem. Int. Ed.2017,56, 3237-3241. (VIP)

41. Yang, Z.-P.; Zheng, C.; Huang, L.; Qian, C.;You, S.-L.*Iridium-Catalyzed Intramolecular Asymmetric Allylic Dearomatization Reaction of Benzoxazoles, Benzothiazoles and Benzimidazoles.Angew. Chem. Int. Ed.2017,56, 1530-1534.

42. Zheng, C.;You, S.-L.*Catalytic Asymmetric Dearomatization (CADA) by Transition-metal-catalysis: A Method for Transformations of Aromatic Compounds.Chem.2016,1, 830-857.

43. Xu, R.-Q.; Yang, P.; Tu, H.-F.; Wang, S.-G.;You, S.-L.*Palladium(0)-Catalyzed Intermolecular Arylative Dearomatization of β-Naphthols.Angew. Chem. Int. Ed.2016,55, 15137-15141.

44. Wang, D.-C.; Xie, M.-S.; Guo, H.-M.*; Qu, G.-R.; Zhang, M.-C.;You, S.-L.*Enantioselective Dearomative [3+2] Cycloaddition Reactions of Benzothiazoles.Angew. Chem. Int. Ed.2016,55, 14111-14115.

45. Huang, L.; Dai, L.-X.;You, S.-L.*Enantioselective Synthesis of Indole-Annulated Medium-Sized Rings.J. Am. Chem. Soc.2016,138, 5793-5796.

46. Ye, K.-Y.; Cheng, Q.; Zhuo, C.-X.; Dai, L.-X.;You, S.-L.*Iridium(I) N-Heterocyclic Carbene Complex Catalyzed Asymmetric Intramolecular Allylic Amination Reactions.Angew. Chem. Int. Ed.2016,55, 8113-8116.

47. Zheng, J.; Cui, W.-J.; Zheng, C.;You, S.-L.*Synthesis and Application of Chiral Spiro Cp Ligands in Rhodium-Catalyzed Asymmetric Oxidative Coupling of Biaryl Compounds with Alkenes.J. Am. Chem. Soc.2016,138, 5242-5245.

48. Wu, Q.-F.; Zheng, C.*; Zhuo, C.-X.;You, S.-L.*Highly Efficient Synthesis and Stereoselective Migration Reactions of Chiral Five-Membered Aza-Spiroindolenines: Scope and Mechanistic Understanding.Chem. Sci.2016,7, 4453-4459.

49. Gao, D.-W.; Gu, Q.;You, S.-L.*An Enantioselective Oxidative C–H/C–H Cross-Coupling Reaction: Highly Efficient Method to Prepare Planar Chiral Ferrocenes.J. Am. Chem. Soc.2016,138, 2544-2547.

50. Cheng, Q.; Wang, Y.;You, S.-L.*Chemo-, Diastereo- and Enantioselective Ir-Catalyzed Allylic Intramolecular Dearomatization Reaction of Naphthol Derivatives.Angew. Chem. Int. Ed.2016,55, 3496-3499.

51. Wu, W.-T.; Xu, R.-Q.; Zhang, L.*;You, S.-L.*Construction of Spirocarbocycles via Gold-Catalyzed Intramolecular Dearomatization of Naphthols.Chem. Sci.2016,7, 3427-3431.

52. Wu, W.-T.; Zhang, L.*;You, S.-L.*Catalytic Asymmetric Dearomatization (CADA) Reactions of Phenol and Aniline DerivativesChem. Soc. Rev.2016,45, 1570-1580.

53. Liu, C.; Yi, J.-C.; Zheng, Z.-B.; Tang, Y.*; Dai, L.-X.;You, S.-L.*Enantioselective Synthesis of 3a-Amino-pyrroloindolines via Copper-Catalyzed Direct Asymmetric Dearomative Amination of Tryptamines.Angew. Chem. Int. Ed.2016,55, 751-754.

54. Yang, Z.-P.; Wu, Q.-F.; Shao, W.;You, S.-L.*Iridium-Catalyzed Intramolecular Asymmetric Allylic Dearomatization Reaction of Pyridines, Pyrazines, Quinolines and Isoquinolines.J. Am. Chem. Soc.2015,137, 15899-15906.

55. Wang, S.-G.; Liu, X.-J.; Zhao, Q.-C.; Zheng, C.; Wang, S.-B.;You, S.-L.*Asymmetric Dearomatization ofβ-Naphthols through a Bifunctional-Thiourea-Catalyzed Michael Reaction.Angew. Chem. Int. Ed.2015,54, 14929-14932.

56. Zhuo, C.-X.; Zhou, Y.; Cheng, Q.; Huang, L.;You, S.-L.*Enantioselective Construction of Spiroindolines with Three Contiguous Stereogenic Centers and Chiral Tryptamine Derivatives: Reactive Spiroindolenine Intermediates.Angew. Chem. Int. Ed.2015,54, 14146-14149.

57. Zhang, X.; Liu, W.-B.; Tu, H.-F.;You, S.-L.*Ligand-Enabled Ir-Catalyzed Intermolecular Diastereoselective and Enantioselective Allylic Alkylation of 3-Substituted Indoles.Chem. Sci.2015,6, 4525-4529.

58. Zhuo, C.-X.; Cheng, Q.; Liu, W.-B.; Zhao, Q.;You, S.-L.*Enantioselective Synthesis of Pyrrole Based Spiro- and Polycyclic Derivatives by Ir-catalyzed Asymmetric Allylic Dearomatization and Controllable Migration Reactions.Angew. Chem. Int. Ed.2015,54, 8475-8479.

59. Li, G.-T.; Gu, Q.;You, S.-L.*Enantioselective Annulation of Enals with 2-Naphthols by Triazolium Salts Derived from L-Phenylalanine.Chem. Sci.2015,6, 4273-4278.

60. Yin, Q.; Wang, S.-G.; Liang, X.-W.; Gao, D.-W.; Zheng, J.;You, S.-L.*Organocatalytic Asymmetric Chlorinative Dearomatization of Naphthols.Chem. Sci.2015,6, 4179-4183.

61. Shao, W.; Li, H.; Liu, C.; Liu, C.-J.*;You, S.-L.*Copper-Catalyzed Intermolecular Asymmetric Propargylic Dearomatization of Indoles.Angew. Chem. Int. Ed.2015,54, 7684-7687.

62.Zheng, J.; Wang, S.-B.; Zheng, C.;You, S.-L.*Asymmetric Dearomatization of Naphthols via a Rh-Catalyzed C(sp2)–H Functionalization/Annulation Reaction.J. Am. Chem. Soc.2015,137, 4880-4883.

63. Zhang, X.; Yang, Z.-P.; Huang, L.;You, S.-L.*Highly Regio- and Enantioselective Synthesis of N-Substituted 2-pyridones via Ir-Catalyzed Intermolecular Asymmetric Allylic Amination.Angew. Chem. Int. Ed.2015,54, 1873-1876.

64. Wang, S.-G.; Yin, Q.; Zhuo, C.-X.;You, S.-L.*Asymmetric Dearomatization of β-Naphthols via Chiral Phosphoric Acid-Catalyzed Amination Reaction.Angew. Chem. Int. Ed.2015,54, 647-650.

65. Zheng, C.*; Zhuo, C.-X.;You, S.-L.*Mechanistic Insights into the Pd-Catalyzed Intermolecular Asymmetric Allylic Dearomatization of Multisubstituted Pyrroles: Understanding the Remarkable Regio- and Enantioselectivity.J. Am. Chem. Soc.2014,136, 16251-16259.

66. Xu, R.-Q.; Gu, Q.; Wu, W.-T.; Zhao, Z.-A.;You, S.-L.*Construction of Erythrinane Skeleton via Pd(0)-Catalyzed Intramolecular Dearomatization ofpara-AminophenolsJ. Am. Chem. Soc.2014,136, 15469-15472.

67. Zheng, J.;You, S.-L.*Construction of Axial Chirality via Rhodium-Catalyzed Asymmetric Dehydrogenative Heck Coupling of Biaryl Compounds with Alkenes.Angew. Chem. Int. Ed.2014,53, 13244-13247.

68. Zhuo, C.-X.; Zheng, C.;You, S.-L.*Transition-metal-catalyzed Asymmetric Allylic Dearomatization ReactionsAcc. Chem. Res.2014,47, 2558-2573.

69. Yang, Z.-P.; Wu, Q.-F.;You, S.-L.*Direct Asymmetric Dearomatization of Pyridines and Pyrazines via Ir-Catalyzed Allylic Amination Reactions.Angew. Chem. Int. Ed.2014,53, 6986-6989.

70. Zhuo, C.-X.; Zhou, Y.;You, S.-L.*Highly Regio- and Enantioselective Synthesis of Poly-Substituted 2H-Pyrroles via Pd-Catalyzed Intermolecular Asymmetric Allylic Dearomatization of PyrrolesJ. Am. Chem. Soc.2014,136, 6590-6593 (selected as JACS Spotlights).

71. Gao, D.-W.; Yin, Q.; Gu, Q.*;You, S.-L.*Enantioselective Synthesis of Planar Chiral Ferrocenes via Pd(0)-Catalyzed Intramolecular Direct C-H Bond ArylationJ. Am. Chem. Soc.2014,136, 4841-4844.

72.Li, W.; Liu, C.; Zhang, H.; Ye, K.; Zhang, G.; Zhang, W.; Duan, Z.;You, S.*; Lei, A.*Palladium-Catalyzed Oxidative C-H/N-H Carbonylation for the Synthesis of β-lactams.Angew. Chem. Int. Ed.2014,53, 2443-2446.

73. Wang, S.-G.;You, S.-L.*Cascade Hydrogenative Dearomatization of Pyridine and Asymmetric aza-Friedel-Crafts Alkylation Reaction.Angew. Chem. Int. Ed.2014,53, 2194-2197.

74. Zhang, X.; Han, L.;You, S.-L.*Ir-Catalyzed Intermolecular Asymmetric Allylic Dearomatization Reaction of Indoles.Chem. Sci.2014,5, 1059-1063.

75. Zhuo, C.-X.;You, S.-L.*Palladium-Catalyzed Intermolecular Asymmetric Allylic Dearomatization Reaction of Naphthol Derivatives.Angew. Chem. Int. Ed.2013,52, 10056-10059.

76. Zhang, X.; Yang, Z.-P.; Liu, C.;You, S.-L.*Ru-Catalyzed Intermolecular Dearomatization Reaction of Indoles with Allylic Alcohols.Chem. Sci.2013,4, 3239-3243.

77. Zhuo, C.-X.; Wu, Q.-F.; Zhao, Q.; Xu, Q.-L.;You, S.-L.*Enantioselective Functionalization of Indoles and Pyrroles via An in-situ Formed Spiro-intermediateJ. Am. Chem. Soc.2013,135, 8169-8172.

78. Gao, D.-W.; Shi, Y.-C.; Gu, Q.*; Zhao, Z.-L.;You, S.-L.*Enantioselective Synthesis of Planar Chiral Ferrocenes via Palladium-catalyzed Direct Coupling with Aryl Boronic AcidsJ. Am. Chem. Soc.2013,135, 86-89.

79. Xu, Q.-L.; Dai, L.-X.;You, S.-L.*Diversity Oriented Synthesis of Indole-based Peri-annulated Compounds via Allylic Alkylation Reactions.Chem. Sci.2013,4, 97-102.

80. Zhuo, C.-X.; Zhang, W.*;You, S.-L.*Catalytic Asymmetric Dearomatization Reactions.Angew. Chem. Int. Ed.2012,51, 12662-12686.

81. Liu, W.-B.; Zhang, X.; Dai, L.-X.;You, S.-L.*Asymmetric N-Allylation of Indoles via Ir-Catalyzed Allylic Alkylation of Indolines and Oxidation Strategy.Angew. Chem. Int. Ed.2012,51, 5183-5187.

82. Liu, W.-B.; Zheng, C.; Zhuo, C.-X.; Dai, L.-X.;You, S.-L.*Ir-Catalyzed Allylic Alkylation Reaction with N-Aryl Phosphoramidite Ligands: Scope and Mechanistic StudiesJ. Am. Chem. Soc.2012,134, 4812-4821.

83. Zheng, C.;You, S.-L.*Transfer Hydrogenation with Hantzsch Esters and Related Organic Hydride DonorsChem. Soc. Rev.2012,41, 2498-2518.(invited paper)

84. Wu, Q.-F.; Zheng, C.;You, S.-L.*Enantioselective Syntheses of Spiro Cyclopentane-1,3'-indoles and 2,3,4,9-Tetrahydro-1H-carbazoles via Ir-Catalyzed Allylic Dearomatization and Stereospecific Migration.Angew. Chem. Int. Ed.2012,51, 1680-1683.

85.Zhuo, C.-X.; Liu, W.-B.; Wu, Q.-F.;You, S.-L.*Asymmetric Dearomatization of Pyrroles via Ir-Catalyzed Allylic Substitution Reaction: Enantioselective Synthesis of Spiro-2H-pyrroles.Chem. Sci.2012,3, 205-208.

86. Ye, K.-Y.; He, H.; Liu, W.-B.; Helmchen, G.; Dai, L-X.;You, S.-L.*Iridium-Catalyzed Allylic Vinylation and Asymmetric Allylic Amination Reactions withortho-AminostyrenesJ. Am. Chem. Soc.2011,133,19006-19014.

87. Cai, Q.; Zheng, C.; Zhang, J.-W.;You, S.-L.*Enantioselective Michael-Mannich Polycyclization Cascade of Indolyl Enones by Quinine-Derived Primary AmineAngew. Chem. Int. Ed.2011,50, 8665-8669.

88. Gu, Q.;You, S.-L.*Desymmetrization of Cyclohexadienones via Cinchonine Derived Thiourea-Catalyzed Enantioselective Aza-Michael Reaction and Total Synthesis of (-)-Mesembrine.Chem. Sci.2011,2, 1519-1522.

89. Yin, Q.;You, S.-L.*Chiral Phosphoric Acid-Catalysed Friedel-Crafts Alkylation Reaction of Indoles with Racemic Spiro Indolin-3-ones.Chem. Sci.2011,2, 1344-1348.

90. Wu, Q.-F.; Liu, W.-B.; Zhuo, C.-X.; Rong, Z.-Q.; Ye, K.-Y.;You, S.-L.*Ir-Catalyzed Intramolecular Asymmetric Allylic Dearomatization of Phenols.Angew. Chem. Int. Ed.2011,50, 4455-4458.

91. Cai, Q.; Zheng, C.;You, S.-L.*Enantioselective Intramolecular Aza-Michael Addition of IndolesCatalyzed byChiral Phosphoric Acid.Angew. Chem. Int. Ed.2010,49, 8666-8669.

92. Wu, Q.-F.; He, H.; Liu, W.-B.;You, S.-L.*Enantioselective Construction of Spiroindolenines by Ir-Catalyzed Allylic Alkylation ReactionsJ. Am. Chem. Soc.2010,132, 11418-11419.

93. Peng, H. M.; Dai, L.-X.;You, S.-L.*Enantioselective Palladium-Catalyzed Direct Alkylation and Olefination Reaction of Simple ArenesAngew. Chem. Int. Ed.2010,49, 5826-5828. (Highlights)

94. Gu, Q.; Rong, Z.-Q.; Zheng, C.;You, S.-L.*Desymmetrization of Cyclohexadienones via Br？nsted Acid-Catalyzed Enantioselective Oxo-Michael ReactionJ. Am. Chem. Soc.2010,132, 4056-4057.

95. He, H.; Liu, W.-B.; Dai, L.-X.;You, S.-L.*Enantioselective Synthesis of 2,3-Dihydro-1H-benzo[b]azepinesvia Ir-Catalyzed Tandem Allylic Vinylation/Amination Reaction.Angew. Chem. Int. Ed.2010,49, 1496-1499.

96. Cai, Q.; Zhao, Z.-A.;You, S.-L.*Asymmetric Construction of Polycyclic Indoles through Olefin Cross-Metathesis/ Intramolecular Friedel-Crafts Alkylation under Sequential Catalysis.Angew. Chem. Int. Ed.2009,48, 7428-7431.

97. He, H.; Liu, W.-B.; Dai, L.-X.;You, S.-L.*Ir-Catalyzed Cross-Coupling of Styrene Derivatives with Allylic Carbonates: Free Amine Assisted Vinyl C-H Bond ActivationJ. Am. Chem. Soc.2009,131, 8346-8347.

98. You, S.-L.*; Cai, Q.; Zeng, M. Chiral Br？nsted Acids Catalyzed Friedel-Crafts Alkylation ReactionChem. Soc. Rev.2009,38, 2190-2201.

99. Kang, Q.; Zhao, Z.-A.;You, S.-L.*Highly Enantioselective Friedel-Crafts Reaction of Indoles with Imines by a Chiral Phosphoric Acid.J. Am. Chem. Soc.2007,129, 1484-1485.

100. You, S.-L.*; Dai, L.-X. Enantioselective Palladium-Catalyzed Decarboxylative Allylic Alkylations.Angew. Chem. Int. Ed.2006,45, 5246-5248.